0000033045 00000 n 0000067714 00000 n 0000019988 00000 n It is debatable, however, if the cat is this study attained a quality of life that warranted keeping her alive. 0000075696 00000 n This condition is due to the dominant gene mutation mentioned above. /MaxWidth 2614 The Scottish Fold is a breed of domestic cat with a natural dominant-gene mutation that affects cartilage throughout the body, causing the ears to "fold", bending forward and down towards the front of the head, which gives the cat what is often described as an "owl-like" appearance.. << �m͆�/�ҋ����)��Q�^�Y������Z�߃G��MF�����0�#�W\�L6U-ِ� �eh��8z ���8�S0�ס�����o0�2�fofws��n�<5���'S���� �a3zV�O�c����F��0�=�!V��l�ͳ��b��������n�{�{K6W�B��b��U�?�j�� �#9�+��(�j~.h���� �݀v�; ^����'a�ϣW�/���Cx�a̗A�W�݌��~�~��_����� �cj�"�Ĵ2k��ẋ9ɼμ�z�U�vv���#��8nJV��m���?R�s+�?�t|�b�{�דh�5y��=�/L�~j��V�PF�Fy?��#p=�x�x�t�a� �8А��V�mx.\x!\K�Z��õ����ڎ����&�%|7�=������4>�/�;�]��@̰ �a&�d�̴�ic0µ�� W?3�l�'�s�9ʼΚ�0�bW����w���ؿs��2\��[��Ƚ���{��D&�Zd�d�^���9����������?U�������)��a�V߇yF��2�W�F����y������K`���bv={�3٥�+��.�2���o����� x)������ݎ���o����9+^̼�cܗ�������Nd?�܍��b~��mx�y����q�9T/{�#{��)�S���zs/T� ss��r�O�e��ߒ]�=��W��q�߱A��|`�xb.a Osteochondrodysplasia is a well-known inherited dis- 0000009435 00000 n 0000012907 00000 n 0000046169 00000 n 0000052147 00000 n 0000017292 00000 n /LastChar 122 0000015215 00000 n Scottish Fold: Lebenserwartung ist abhängig von Therapie. 10 0 obj Taylor Swift besitzt gleich zwei. The Scottish fold cat breed has small ears that are folded forward. Sie wird heute aufgrund der unterschiedlichen Anerkennung durch Zuchtverbände weltweit haup… /Ascent 891 Case 1 is a mixed Scottish Fold and Munchkin cat. )}��ê���]����q�Fn���\�ѩS��"�Z�����͞��­����|N*y�7�����P�hu�G֜ˣ1Z���/�aX\%�H��0�:⭩C�V�A1�uc�5���eê��]|=����,��]A����~>eE9E���H�@�9@����p"1\QA D�O�8���S�-��p��!��C���+��3��~?y���Jh%�-�*݋h�{I�D�0�GrƦs�KH��tι�}A��C��1�ae�ܟ���[��c������߾(ؾpy�ز�����?wWʯ;�W��R,�0���лpyI�?Y�5�rY��j0�asS�f�K1��Ҧ ~/>�2��Ғ�������Q� ��`�u��S��~������R��U+�i�>��������X0a�/ߵK���V@V�v���]}�V�N ��|p�Q�������7��G����n��&��h3h�� �u� ߺhy�Q��[w�0�i��} y]GA"�h*CRI"�� �=�#���waq��r4�ޯň�)��0Z5ʔ��RGڑ�v�(Wʑ�Ks��,� �J�ʥ��Ó�c�?���A1M����#�S ��U摁�. >> 0000075042 00000 n 0000070849 00000 n It is this that causes the abnormal ear shape in Scottish fold cats. However, they tend to develop osteochondrodysplasia more than other cat breeds because of the characteristic ears. << 0000003650 00000 n Osteochondrodysplasia in Scottish Fold cats. >> Osteochondrodysplasia is a painful, progressive clinical syndrome unique to Scottish fold cats because of a heritable missense mutation in the TRPV4 gene. /Type /FontDescriptor The ear pinna were curled caudally like the American Curl. A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats. 0000051612 00000 n 0000051639 00000 n 0000062645 00000 n /ItalicAngle 0 The disease can be apparent in animals as young as 7 week… 0000070100 00000 n %%EOF /Type /ExtGState 0000068012 00000 n /BaseFont /Times#20New#20Roman The disease is evident on … It was discovered that if a folded ear Scottish fold was bred to another folded ear, many of the offspring developed a severe crippling lameness early in life. The Scottish Fold is a purebred cat with forward-folded ears, autosomal-dominant inherited trait and an outward sign of generalized defective cartilage formation [1, 7, 8].Scottish Fold osteochondrodysplasia (SFOCD) is an inheritable disorder characterized by skeletal deformities such as short, thick, and inflexible tails and shortened splayed feet [1, 2, 6]. 0000124510 00000 n 0000050997 00000 n 0000036365 00000 n 0000113209 00000 n Two Scottish Fold mixed cats are described in this report. 0000007574 00000 n Originally called lop-eared or lops after the lop-eared rabbit, Scottish Fold became the breed's name in 1966. Design Retrospective study of cases seen in five veterinary clinics and radiographic survey of cats in a cattery. A 3‐year‐old female spayed Scottish Fold cat suffering from osteochondrodysplasia was referred to the Veterinary Teaching Hospital, University of Zurich. << 0000008845 00000 n “the Fold Gene”), as discovered by Barbara Gandolfi together with a team of researchers in 2016 and reported in this paper.A kitten inherits two genes from their parents and only one of them has to be a Fold gene in order for their ears to fold. 0000091073 00000 n 0000002940 00000 n Die Anschaffungskosten für eine Scottish Fold Katze liegen zwischen 500 und 1.300 Euro. Results Six Scottish Fold cats (four castrated males, two spayed females) aged between 5 months and 6 years were presented for signs of skeletal disease including lameness, reluctance to jump, a stiff stilted gait, short misshapen distal limbs, swelling of plantar tarsometatarsal regions and short thick inflexible tails. /Subtype /TrueType 0000006937 00000 n /FontBBox [-568 -216 2046 693] 0000041171 00000 n �*z]���6�CՓ0�Z�~�PS�M X��M���,zD!�3�|�G vo�.e�0�8���^,�����3�/�^�X*Κ�0��PW[��UWUf3�T2Q�E#�P0����v9v��l2��N�Q�� 0000019874 00000 n 0000005740 00000 n 0000045586 00000 n 0000006696 00000 n /Length1 35716 /Leading 42 The Scottis… << 0000014392 00000 n Known for being a warm, attentive cat, its ear fold … >> /FontName /Times#20New#20Roman Homozygous (Fd/Fd) individuals have severe disease. 0000006211 00000 n It is characterised by skeletal deformities which include folded ears, short, thick and inflexible tails, abnormal feet and joints, and fusion of the bones in severely affected cats. 0000063625 00000 n 0000004273 00000 n 13 0 obj Osteochondrodysplasia. Key words: osteochondrodysplasia, Scottish Fold cat Introduction The breed “Scottish fold cat” is a domestic breed with an autosomal dominant gene mutation which affects the cartilage tissue in the whole body. In this post, I’ll explain about osteochondrodysplasia. 0000063776 00000 n 0000100712 00000 n 0000067241 00000 n ��|�k���. Dank ihrer berühmten Besitzerin sind Meredith und Olivia derzeit sicherlich die bekanntesten Scottish-Fold-Katzen. Die Standards der Rassekatzen werden von der FIFe = "Féederation Internationale Féline" vorgegeben. 0000020877 00000 n Scottish Fold Katzen haben eine dominant vererbte Osteochondrodysplasie. /Length 24998 itemprop="description. 0000067514 00000 n x���xչ z��lo�����]m��+ie�;��mYX�M2� 0X�p,B16;��`�P$��l bHH��$� 7'�!P�pR@���ٕ1����}�{;:eN?g����a�� !Ie��˺�@ʏ���ڲId���E'R�����=�FH�EH~���[/}���N�� ��ukV�����mA��u�`�P� ��}hݕ�����ܷ��B�e��U+N/� t�]���W���_��߆е"��Zq���3`,�J����MS!���>%���k�݇�E�z�ab��;��Sc�&hE-�h��ĩOe�O��j�?#!<55���'�!��� .��w!X��߀; ��yP� 0000017833 00000 n 0000013294 00000 n Because of its sweet appearance and friendly personal-ity,7 the SF is one of the popular breeds in Japan. <]/Prev 850170/XRefStm 2751>> Fold Scottish Fold PO Orally SFOCD Scottish Fold osteochondrodysplasia SC Subcutaneously Although fold-eared cats were first (prick, pert or upright) ears from this T he Scottish Fold is one of the rarest purebred cats in Australia. 0000012634 00000 n Based on the breed, history, clinical signs, radiographic findings, and the histologic diagnosis of a biopsy specimen, Scottish Fold osteochondrodysplasia was confirmed. 0000063205 00000 n /FontWeight 400 0000003087 00000 n 0000021776 00000 n Osteochondrodysplasia in Scottish Fold cats R MALIKa, GS ALLANa, CR HOWLETTb, DE THOMPSONc, G JAMESd, C McWHIRTEReand K KENDALLf Objective To better characterise the bone and joint problems which can develop in Scottish Fold cats. 19 0 obj %PDF-1.4 %���� 0000046099 00000 n /FontDescriptor 10 0 R /StemV 40 Related terms: Scottish fold osteodystrophyOutline: Osteochondrodysplasia is a developmental abnormality that affects cartilage throughout the body. 0000019070 00000 n /CapHeight 693 0000002158 00000 n Da eine dauerhafte Versorgung durch den Tierarzt zu erwarten ist, sollten diese Kosten ebenfalls entsprechend berücksichtigt werden. 0 0000052249 00000 n Dieses Merkmal ist das Ergebnis einer stabilen und vererbbaren Mutation. 0000019502 00000 n 0000011001 00000 n 0000008358 00000 n << 0000045759 00000 n 0000046250 00000 n ;������\�^Dchz5�NtjC���H���!Q3z���Ԋ�X��Go��� �:�b�����ԏl�0�>���֩�PJ���w�1�/B��a�8=�i�Ql���p�U�;�:��@�]dDQ�}����SdECh%z_��G~ԇn�rܮ�+�t��C�m���:��C�o`;�zg���Fk��/�[a�#h�I�M�}�b4]�V@�u�Mlƕ�4��=u?�>�>b�ˬƑ@sQ/������4������?�ހ�����Z�ӯ��=��BGq%�d�Vˎ�h ��F�@��I܎��~�}D��,NY��S��gY��`�{���Y��2�`7q>n��j���j�:�~ /XHeight 250 /Descent -216 trailer Die Schottische Faltohrkatze (Scottish Fold) ist eine Kurzhaarkatze, deren Hauptmerkmal nach vorne hängende Ohren, so genannte Faltohren, sind. 631 0 obj <>stream Die Katzenrasse Scottish Fold entstand durch züchterische Bemühungen ab Anfang der 1960er-Jahre in Großbritannien. 0000045786 00000 n 0000067687 00000 n Scottish Fold osteochondrodysplasia or SF OCD is caused by a mutation of the TRPV4 gene (a.k.a. /Type /ExtGState /BM /Normal Osteochondrodysplasia is a disorder (”dysplasia”) of bones (”osteo”) and cartilage (”chondro”). 0000011572 00000 n 9 0 obj Auch die sozialen Medien haben feline Promis dieser Rasse: Instagram-Star Shrampton hat 50 000, Nana 135 000 und Muta gar über 300 000 Abonnenten. Kirsten Dunst, Mia Farrow, Patrick Dempsey und Ed Sheeran haben sie. /BM /Normal endobj Case 2 is a mixed Scottish Fold and American Curl cat. 0000010531 00000 n %���� Scottish Fold Katzenzüchter versuchen schon ein halbes Jahrhundert vergeblich, gesunde Scottish Fold Katzen zu züchten. ��5��_��p\�a��l�Z6����`,J$�:�-G�t5�:�q�g� ����r/ɮ���� ��c��-��>q8�7�E�s��}p$�8/�oX���ϗ�h1��%%(y�?��J%�s%1/6��TRl ��'���(^���_jv���4�A�{h\q�*�-�u��0�[�[�������Ш��Mkԩ$:��@T�a{�� ���4��[�0H��A ���-��`3�0nY�z�saWK����N%�qӪ��a�=lH�"��v3,oV�n���l�m��خ�Gy��/�]\���avE7�Ø�~���מv|v����v���fw�8.���];��}�������f­}�Z���a ���ssw�0�:�l! 0000006808 00000 n 0000112469 00000 n An 8 yr old male neutered Scottish fold cat was presented for a mass on his hind paw. /Widths 11 0 R Anahtar sözcükler: Scottish Fold osteokondrodisplazi, Kedi Hereditary Osteochondrodysplasia in Scottish Fold Cats [1] [2] Didar AYDIN 1 Kemal ALTUNATMAZ 1 Dilek OLĞUN ERDİKMEN 1 Kürşat ÖZER 1 Damla DURMUŞ 1 Kozet AVANUS 2 [1] [2] 1 2 This study has been supported by Istanbul University Research Found Project number: UDP-52479 In one of the newer studies available online Osteochondrodysplasia in a 9-Year-Old Scottish Fold Cat (view source), an older cat with crippling OCD could be helped somewhat with prednisolone in 2016. As all Scottish Fold cats suffered from osteochondrodysplasia of some degree, the best solution would be to avoid using fold-eared cats for breeding and instead use Scottish shorthairs. This inherited cartilage defect (also known as Scottish Fold disease, or Osteochondrodysplasia) causes other deformities throughout the body and is a dominant trait, meaning all kittens in the litter will be affected. [250 0 408 0 0 833 778 180 333 333 500 564 250 333 250 278 500 500 500 500 500 500 500 500 500 500 278 278 564 564 564 444 921 722 667 667 722 611 556 722 722 333 389 722 611 889 722 722 556 722 667 556 611 722 722 944 722 722 611 333 0 333 469 500 333 444 500 444 500 444 333 500 500 278 278 500 278 778 500 500 500 500 333 389 278 500 500 722 500 500 444] 12 0 obj xref /Encoding /WinAnsiEncoding 541 0 obj <> endobj 0000051267 00000 n Man kann drei Hauptgruppen unterscheiden: 1. robuster Typ (rechteckiger oder runder Kopf, gedrungener Körper, kurze und kräftige Beine / Eindruck: mächtig und imponierend) 2. muskulöser Typ (runder Kopf, mittelgroßer Körper, langer und mitteldicker Schwanz / Eindruck: agil und kräftig) 3. schlanker Typ (dreieckiger Kopf, sch… 17 0 obj /Flags 32 Scottish Fold Osteochondrodysplasia is a genetic disorder of bone and cartilage. 0000041252 00000 n %PDF-1.6 The problem is that it also affects other parts of the body. It is so sad to realize that the unique looking ears represent in fact a serious health condition. The most obvious outward manifestation of this is making the ear cartilage fold so the ears bend forward, giving the cat its characteristic appearance. Wie lange leben Scottish Fold Katzen? 0000124768 00000 n Osteochondrodysplasia in Scottish Fold Cats. Its effects in other parts of the body, especially the limb bones, are much more serious, causing severe distortion of limb bone shapes and severe arthritis. It is most commonly manifested as the distortion of limb bone shapes and severe arthritis. h�b```b`������ "� Ā Bl@Q�U� >��{~v����ɷk@��. 0000100302 00000 n /Supplement 0 endobj /Ordering (Identity) It can also manifest from as early as 7-8 weeks of age. endobj 0000062914 00000 n >��?�m��砷 �������gɞA��_�,N�>�d��� stream 0000090420 00000 n Most of the cats with severe osteochondrodysplasia showed some clinical signs, but cats with mild disease were clinically unaffected. 0000018172 00000 n 0000012769 00000 n The special health condition that needs to be considered when adopting a Scottish Fold cat or kitten is related directly to the ears that make them so stunning and unique: Osteochondrodysplasia. 0000027936 00000 n It belongs in a wider group of disorders, generally known as osteochondrodysplasia, but the form occurring in the Scottish Fold breed is specific by its causative mutation. /Registry (Adobe) 0000017434 00000 n startxref It is what gives them the distinct ear shape. Osteochondrodysplasia is a disease that is unique to Scottish Folds. 0000009525 00000 n >> >> That is the reason of the breed’s appearance – the folded ears. << /Filter /FlateDecode 0000045319 00000 n endobj 0000005073 00000 n /CA 1 It can be characterized into group of musculoskeletal disorders, a broad category of diseases that affects the muscles or bones. 0000000016 00000 n 0000090669 00000 n 0000075298 00000 n 0000063232 00000 n Known for being a warm, attentive cat, its ear fold gene increases risk for disease." /FirstChar 32 11 0 obj Extremities of this cat resembled the Munchkin cat, while the ear pinna were folded forward like the Scottish Fold cat. 0000052077 00000 n 0000063695 00000 n 0000070450 00000 n Diese Studie zielt darauf ab, das Gen und die zugrunde liegende Variante für die Osteochondrodysplasie zu identifizieren. endobj Cats affected had shortened, malformed legs and tail as well as abnormalities affecting the growth plates and spine. All Scottish Fold-related cats with folded-ear phenotype, even if heterozygotes, suffered from some degree of osteochondrodysplasia of the distal limbs. Scottish Fold osteochondrodysplasia is an inherited bone and cartilage disorder specific for this cat breed. Also known as Scottish Fold osteochondrodysplasia (SFOCD), osteodystrophy is an inherited condition which affects cartilage and bone throughout the body. 0000112729 00000 n /AvgWidth 401 0000016240 00000 n The bread and butter disease. Chondrodysplasia and osteochondrodysplasia result in disproportionate dwarfism and have been reported in a number of breeds, including Alaskan malamutes, Norwegian elkhounds, Great Pyrenees, Scottish deerhounds, bull terriers, and Scottish fold cats. EZ��-١2[�8�^``h\yk�;>�#�0!�]���+����p��|ow6��8s$�Ä0&%�[�N�X�,*D�M��.���ixo�A!�c��8����uK}�]P���Ɵ�0� Ǥm�b2L�XEL Scottish Fold disease – osteochondrodysplasia 05th September 2018 The Scottish Fold breed of cat has a genetic mutation that affects the development of cartilage. Scottish Fold cats are known for its folded ears and one of the most popular cat breed. 0000002751 00000 n >> 0000010432 00000 n Osteochondrodysplasia in Scottish folds is an autosomal dominant condition with high but incomplete penetrance. �I��؇�� ��w# ?��ƣ�����|FOk���Z �'X?~�U�n2Fa���9�,a���:�K�]�Y�ؙ�M��`��D�� 6�9�Bt/������-{Cv����$�eQ�#T{�wpu�[P:0x+�2��맆�j���?4�/G�li��mzac�{�׿��!`�v�Gt5ag��Grn�Z 3��� �ը�B_���-�v�8q�a��_�K���'��B 0���k\F-f�M��(��� ��y'70�=S��/5h�+販{Q�n�� �N}m�b�-�z�T�vȺ����� endobj registered in 1972.7–9 Scottish Fold cats have a charac-teristic appearances that include folded-ears, large round eyes, a gentle nose curve, and thick, short limbs. The biggest health concern for Scottish folds is a degenerative joint disease called osteochondrodysplasia that affects cartilage and bone development due to the fold gene. 0000017155 00000 n /ca 1 541 91 0000041101 00000 n 0000009939 00000 n The Scottish fold cat breed has small ears that are folded forward. /Type /Font 0000100036 00000 n 0000008259 00000 n